VCWG
Entomology Research
Anopheles: Epidemiological/Entomological Research

Accurately evaluating the effectiveness and efficacy of both current and new vector control tools and approaches is crucial for monitoring and reducing the risk and burden of vector-borne disease in endemic settings. Demonstrating the current, and predicting future, impact of current tools in any setting  should be carried out through an assessment of both the vector and human populations within specific locations, taking into account both local conditions, structures, and practices related to disease control. For the introduction of new vector control tools and strategies, the WHO recommends that products are trialled under Phase III conditions with clear epidemiological endpoints before they can enter phase VI trials under ‘real world’ operational conditions.

This section provides guidance and toolkits for planning, designing, and implementing both entomological and epidemiological research to measure and document the effectiveness, and efficacy of different vector control tools within different environments/conditions. 

WHO Guidance for Phase III Vector Control Efficacy Trials
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Improving Quality of Vector Control Trials
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Entomology Research Trial Design: Further Resources
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WHO Guidance on Epidemiological Trials for Vector Control Products
Download PDF
WHO Guidance for Epidemiological Approaches to Malaria Control
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Epidemiological and Entomological Tools for Malaria Control
Download PDF
Selecting Study Design Methods for MMP Groups
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Entomology Research

Accurately evaluating the effectiveness and efficacy of both current and new vector control tools and approaches is crucial for monitoring and reducing the risk and burden of vector-borne disease in endemic settings. Demonstrating the current, and predicting future, impact of current tools in any setting  should be carried out through an assessment of both the vector and human populations within specific locations, taking into account both local conditions, structures, and practices related to disease control. For the introduction of new vector control tools and strategies, the WHO recommends that products are trialled under Phase III conditions with clear epidemiological endpoints before they can enter phase VI trials under ‘real world’ operational conditions.

This section provides guidance and toolkits for planning, designing, and implementing both entomological and epidemiological research to measure and document the effectiveness, and efficacy of different vector control tools within different environments/conditions. 

WHO Guidance for Phase III Vector Control Efficacy Trials
Download PDF
Improving Quality of Vector Control Trials
Download PDF
Entomology Research Trial Design: Further Resources
Visit website
Anopheles: Epidemiological/Entomological Research
WHO Guidance on Epidemiological Trials for Vector Control Products
Download PDF
WHO Guidance for Epidemiological Approaches to Malaria Control
Download PDF
Epidemiological and Entomological Tools for Malaria Control
Download PDF
Selecting Study Design Methods for MMP Groups
Download PDF